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If you are always tired? Suspect “Hypoadrenal Insufficiency”. From symptoms to causes and treatments
If chronic fatigue continues and you have lost your appetite, you may suspect “Hypoadrenal Insufficiency”. I will tell you about what hypoadrenal insufficiency is, its causes, symptoms, and treatments.
The adrenal glands are endocrine organs located above both kidneys and are one of the most important organs for maintaining life. This is because they secrete a hormone called “cortisol” that counteracts various stresses. If the adrenal function decreases due to autoimmune disease, tumor, genetics, etc. and this hormone is deficient, the body’s balance may be disrupted and symptoms such as fatigue, loss of appetite, and nausea may occur because the body is unable to respond appropriately when mental and physical stress occurs.
It can be broadly divided into primary hypoadrenal insufficiency and secondary hypoadrenal insufficiency. Primary adrenal insufficiency is caused by problems with the adrenal gland itself, and can be caused by adrenal tuberculosis, autoimmune diseases, adrenal tumors, cancer metastasized from other organs, and rarely, bleeding or congenital diseases.
Secondary adrenal insufficiency is caused by a deficiency in the secretion of adrenocorticotropic hormone, which stimulates the secretion of cortisol in the brain. It can occur after a tumor in the pituitary gland or hypothalamus or surgery for a pituitary adenoma, and can also occur after long-term steroid administration.
Representative symptoms of adrenal insufficiency include general weakness, decreased appetite, fatigue, and gastrointestinal symptoms (nausea, vomiting, constipation, diarrhea). Weight loss, hypoglycemia, hypotension, alopecia, muscle or joint pain, etc. may also occur, and primary adrenal insufficiency is characterized by hyperpigmentation of the skin. If the disease progresses rapidly (adrenal crisis), abdominal pain, fever, cramps, severe dehydration, and electrolyte abnormalities may occur, and in severe cases, loss of consciousness, shock, and even death may occur.
Blood tests are used to measure electrolyte, cortisol, and adrenocorticotropic hormone concentrations, and additional CT or MRI tests may be performed depending on the results.
To treat adrenal insufficiency, supplement the hormones that are lacking in the body with steroids (such as hydrocortisone or prednisolone). In stressful situations such as surgery, trauma, fever, and infection, the dosage of the medication being taken may need to be increased, so consultation with the attending physician is necessary.
In acute adrenal insufficiency such as adrenal crisis, hydrocortisone is administered intravenously, and dehydration, electrolyte abnormalities, and low blood pressure are corrected with fluid and glucose injections.
Since cortisol normally increases in response to stress, patients with adrenal insufficiency may experience more severe hormone deficiency symptoms in stressful situations such as surgery, trauma, fever, and infection. Therefore, in such situations, you should increase the dose of steroids by 2-3 times from the previous dose, and if you cannot take the medication under severe stress, you should visit the emergency room and receive steroid injections.
Do you have any further questions about adrenal insufficiency? Try Doctor Now’s real-time free consultation service. Professional medical staff will answer your questions 24 hours a day for free. You can also receive answers to questions about other diseases within 5 minutes, so click the button below to use it.
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As many of you may know,
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